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Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

Angiotensin II receptor type 1 and 2 (AT1R and AT2R) are two G-protein coupled receptors that mediate most biological functions of the octapeptide Angiotensin II (Ang II). AT2R is upregulated upon tissue damage and its activation by selective AT2R agonists has become a promising approach in the sear...

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Detalles Bibliográficos
Autores principales: Vasile, Silvana, Hallberg, Anders, Sallander, Jessica, Hallberg, Mathias, Åqvist, Johan, Gutiérrez-de-Terán, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226584/
https://www.ncbi.nlm.nih.gov/pubmed/32340100
http://dx.doi.org/10.3390/biom10040649