Analysis of BRCA1 and RAD51C Promoter Methylation in Italian Families at High-Risk of Breast and Ovarian Cancer

Previous studies on breast and ovarian carcinoma (BC and OC) revealed constitutional BRCA1 and RAD51C promoter hypermethylation as epigenetic alterations leading to tumor predisposition. Nevertheless, the impact of epimutations at these genes is still debated. One hundred and eight women affected by...

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Detalles Bibliográficos
Autores principales: Tabano, Silvia, Azzollini, Jacopo, Pesenti, Chiara, Lovati, Sara, Costanza, Jole, Fontana, Laura, Peissel, Bernard, Miozzo, Monica, Manoukian, Siranoush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226593/
https://www.ncbi.nlm.nih.gov/pubmed/32276467
http://dx.doi.org/10.3390/cancers12040910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226593/
https://www.ncbi.nlm.nih.gov/pubmed/32276467
http://dx.doi.org/10.3390/cancers12040910

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