Cargando…
Molecular Regulation of the RhoGAP GRAF3 and Its Capacity to Limit Blood Pressure In Vivo
Anti-hypertensive therapies are usually prescribed empirically and are often ineffective. Given the prevalence and deleterious outcomes of hypertension (HTN), improved strategies are needed. We reported that the Rho-GAP GRAF3 is selectively expressed in smooth muscle cells (SMC) and controls blood p...
Autores principales: | Dee, Rachel A., Bai, Xue, Mack, Christopher P., Taylor, Joan M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226614/ https://www.ncbi.nlm.nih.gov/pubmed/32331391 http://dx.doi.org/10.3390/cells9041042 |
Ejemplares similares
-
The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension
por: Bai, Xue, et al.
Publicado: (2013) -
Turning RacGAP into a RhoGAP
por: Tuma, Rabiya S.
Publicado: (2003) -
SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP
por: Chau, Jocelyn E., et al.
Publicado: (2022) -
Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype
por: Regev, Miriam, et al.
Publicado: (2016) -
Characterization of the Rho GTPase-Activating Protein RhoGAP68F
por: Nahm, Minyeop, et al.
Publicado: (2011)