Cargando…

Interferon Alpha Therapy Increases Pro-Thrombotic Biomarkers in Patients with Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPN) are associated with an increased risk of arterial and venous thrombosis. Pegylated-interferon alpha (IFN) and hydroxyurea (HU) are commonly used to treat MPN, but their effect on hemostasis has not yet been studied. The aim of our study was to determine whether IFN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faille, Dorothée, Lamrani, Lamia, Loyau, Stéphane, Huisse, Marie-Geneviève, Bourrienne, Marie-Charlotte, Alkhaier, Sawsaneh, Cassinat, Bruno, Boulaftali, Yacine, Debus, Jérôme, Jandrot-Perrus, Martine, Chomienne, Christine, Dosquet, Christine, Ajzenberg, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226618/ https://www.ncbi.nlm.nih.gov/pubmed/32316612 http://dx.doi.org/10.3390/cancers12040992

Ejemplares similares

Glycoprotein VI in securing vascular integrity in inflamed vessels
por: Boulaftali, Yacine, et al.
Publicado: (2018)

Vascular endothelial cell expression of JAK2(V617F) is sufficient to promote a pro-thrombotic state due to increased P-selectin expression
por: Guy, Alexandre, et al.
Publicado: (2019)

Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan
por: Jiang, Peng, et al.
Publicado: (2015)

Collagen Can Selectively Trigger a Platelet Secretory Phenotype via Glycoprotein VI
por: Ollivier, Véronique, et al.
Publicado: (2014)

Heparin-induced Thrombocytopenia Diagnosis: A Retrospective Study Comparing Heparin-induced Platelet Activation Test to (14) C-serotonin Release Assay
por: Gonthier, Marie-Caroline, et al.
Publicado: (2021)

State of the art in cerebral venous sinus thrombosis animal models
por: Bourrienne, Marie‐Charlotte, et al.
Publicado: (2022)

Biomarkers for the risk of thrombosis in pancreatic adenocarcinoma are related to cancer process
por: Faille, Dorothée, et al.
Publicado: (2018)

Anemia and hemodilution: analysis of a single center cohort based on 2,858 red cell mass measurements
por: Drevon, Louis, et al.
Publicado: (2021)

When hemolysis masks polycythemia vera
por: Derrieux, Coralie, et al.
Publicado: (2019)

Does increasing the JAK2V617F assay sensitivity allow to identify more patients with MPN?
por: Kouroupi, E, et al.
Publicado: (2012)

Defining the Thrombotic Risk in Patients with Myeloproliferative Neoplasms
por: Vianello, Fabrizio, et al.
Publicado: (2011)

Thrombotic and Hemorrhagic Issues Associated with Myeloproliferative Neoplasms
por: Papageorgiou, Loula, et al.
Publicado: (2022)

Myocardial infarction as a thrombotic complication of myeloproliferative disorders
por: Petrou, Emmanouil, et al.
Publicado: (2016)

Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion
por: Selbonne, Sonia, et al.
Publicado: (2021)

The (Fab)ulous Destiny of Idarucizumab: Highlighting Its Interference with Urine Protein Immunofixation
por: Gendron, Nicolas, et al.
Publicado: (2019)

Intensified thromboprophylaxis in COVID-19 critically ill patients: Is it enough?
por: de Montmollin, Etienne, et al.
Publicado: (2021)

Role of the microenvironment in myeloid malignancies
por: Goulard, Marie, et al.
Publicado: (2017)

Molecular Genetics of Thrombotic Myeloproliferative Neoplasms: Implications in Precision Oncology
por: Chia, Yuh Cai, et al.
Publicado: (2023)

Interlaboratory Development and Validation of a HRM Method Applied to the Detection of JAK2 Exon 12 Mutations in Polycythemia Vera Patients
por: Ugo, Valerie, et al.
Publicado: (2010)

Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen‐Induced Platelet Aggregation
por: Renaud, Lionel, et al.
Publicado: (2020)

Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks
por: Lebozec, Kristell, et al.
Publicado: (2017)

Non-Invasive Molecular Imaging of Fibrosis Using a Collagen-Targeted Peptidomimetic of the Platelet Collagen Receptor Glycoprotein VI
por: Muzard, Julien, et al.
Publicado: (2009)

Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition
por: Billiald, Philippe, et al.
Publicado: (2022)

SARS-CoV-2 vaccination and thrombotic risk in myeloproliferative neoplasms
por: Borsani, Oscar, et al.
Publicado: (2023)

Neuron-Specific Enolase Levels in Adults Under Venoarterial Extracorporeal Membrane Oxygenation
por: Reuter, Jean, et al.
Publicado: (2020)

Benefits and pitfalls of pegylated interferon-α2a therapy in patients with myeloproliferative neoplasm-associated myelofibrosis: a French Intergroup of Myeloproliferative neoplasms (FIM) study
por: Ianotto, Jean-Christophe, et al.
Publicado: (2018)

Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye
por: Maupu, Clémence, et al.
Publicado: (2022)

CCND2 mutations are infrequent events in BCR-ABL1 negative myeloproliferative neoplasm patients
por: Cassinat, Bruno, et al.
Publicado: (2020)

Clonal architecture evolution in Myeloproliferative Neoplasms: from a driver mutation to a complex heterogeneous mutational and phenotypic landscape
por: Maslah, Nabih, et al.
Publicado: (2023)

Novel ELISA for the specific detection of protease NEXIN‐1 in human biological samples
por: Venisse, Laurence, et al.
Publicado: (2022)

Thrombotic and hemorrhagic events in 2016 World Health Organization-defined Philadelphia- negative myeloproliferative neoplasm
por: Song, Ik-Chan, et al.
Publicado: (2021)

Dabigatran-reversal failure using standard dose of idarucizumab: a systematic review and meta-analysis of cases
por: Melicine, Sophie, et al.
Publicado: (2023)

Arterial Thrombotic Events in Adult Inpatients With COVID-19
por: Fournier, Morgane, et al.
Publicado: (2021)

Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins
por: Chanet, Roland, et al.
Publicado: (2015)

Glenzocimab does not impact glycoprotein VI-dependent inflammatory hemostasis
por: Jadoui, Soumaya, et al.
Publicado: (2020)

Platelets Are at the Nexus of Vascular Diseases
por: Lebas, Héloïse, et al.
Publicado: (2019)

Immobilized fibrinogen activates human platelets through glycoprotein VI
por: Mangin, Pierre H, et al.
Publicado: (2018)

Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression
por: Klein, Claudius, et al.
Publicado: (2016)

Renal thrombotic microangiopathy and FIP1L1/PDGFRα-associated myeloproliferative variant of hypereosinophilic syndrome
por: Langlois, Anne Lyse, et al.
Publicado: (2013)

Genetic Polymorphisms of Hemostatic Factors and Thrombotic Risk in Non BCR-ABL Myeloproliferative Neoplasms: A Pilot Study
por: Dambrauskienė, R, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_g20ktibcrfqu5plbga4j0k8qkn