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An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report

INTRODUCTION: Upper gastrointestinal bleeding (UGIB) in patients suffering from hepatocellular carcinoma (HCC) is usually due to oesophageal or gastric varices secondary to portal hypertension. Very rarely, HCC can directly invade into the stomach or duodenum resulting in UGIB. PRESENTATION OF CASE:...

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Autores principales: Liu, Yuk Ho, Lo, Eugene Yee Juen, Lee, Kit Fai, Chong, Charing Ching Ning, Lai, Paul Bo San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226638/
https://www.ncbi.nlm.nih.gov/pubmed/32416488
http://dx.doi.org/10.1016/j.ijscr.2020.04.008
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author Liu, Yuk Ho
Lo, Eugene Yee Juen
Lee, Kit Fai
Chong, Charing Ching Ning
Lai, Paul Bo San
author_facet Liu, Yuk Ho
Lo, Eugene Yee Juen
Lee, Kit Fai
Chong, Charing Ching Ning
Lai, Paul Bo San
author_sort Liu, Yuk Ho
collection PubMed
description INTRODUCTION: Upper gastrointestinal bleeding (UGIB) in patients suffering from hepatocellular carcinoma (HCC) is usually due to oesophageal or gastric varices secondary to portal hypertension. Very rarely, HCC can directly invade into the stomach or duodenum resulting in UGIB. PRESENTATION OF CASE: A 62-year-old man presented to the emergency department for haematemesis and tarry stool. He was a hepatitis B carrier and had received open radiofrequency ablation and wedge resection for HCC previously. Urgent endoscopy and contrast computed tomography confirmed recurrent HCC invading into the duodenum. The patient received radical resection and remained disease free for 7 years after the operation. DISCUSSION: Direct invasion into gastrointestinal tract by HCC is rare. Different modalities of treatment have been reported in the literature with variable success. En-bloc resection should be considered if surgically feasible in order to achieve good haemostasis and possible long term survival. CONCLUSION: Upper gastrointestinal bleeding is a rare presentation of hepatocellular carcinoma and long term survival can be achieved by curative surgery.
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spelling pubmed-72266382020-05-18 An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report Liu, Yuk Ho Lo, Eugene Yee Juen Lee, Kit Fai Chong, Charing Ching Ning Lai, Paul Bo San Int J Surg Case Rep Article INTRODUCTION: Upper gastrointestinal bleeding (UGIB) in patients suffering from hepatocellular carcinoma (HCC) is usually due to oesophageal or gastric varices secondary to portal hypertension. Very rarely, HCC can directly invade into the stomach or duodenum resulting in UGIB. PRESENTATION OF CASE: A 62-year-old man presented to the emergency department for haematemesis and tarry stool. He was a hepatitis B carrier and had received open radiofrequency ablation and wedge resection for HCC previously. Urgent endoscopy and contrast computed tomography confirmed recurrent HCC invading into the duodenum. The patient received radical resection and remained disease free for 7 years after the operation. DISCUSSION: Direct invasion into gastrointestinal tract by HCC is rare. Different modalities of treatment have been reported in the literature with variable success. En-bloc resection should be considered if surgically feasible in order to achieve good haemostasis and possible long term survival. CONCLUSION: Upper gastrointestinal bleeding is a rare presentation of hepatocellular carcinoma and long term survival can be achieved by curative surgery. Elsevier 2020-05-11 /pmc/articles/PMC7226638/ /pubmed/32416488 http://dx.doi.org/10.1016/j.ijscr.2020.04.008 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Yuk Ho
Lo, Eugene Yee Juen
Lee, Kit Fai
Chong, Charing Ching Ning
Lai, Paul Bo San
An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title_full An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title_fullStr An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title_full_unstemmed An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title_short An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report
title_sort unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226638/
https://www.ncbi.nlm.nih.gov/pubmed/32416488
http://dx.doi.org/10.1016/j.ijscr.2020.04.008
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