Acid Sphingomyelinase Downregulation Enhances Mitochondrial Fusion and Promotes Oxidative Metabolism in a Mouse Model of Melanoma

Melanoma is the most severe type of skin cancer. Its unique and heterogeneous metabolism, relying on both glycolysis and oxidative phosphorylation, allows it to adapt to disparate conditions. Mitochondrial function is strictly interconnected with mitochondrial dynamics and both are fundamental in tu...

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Detalles Bibliográficos
Autores principales: Coazzoli, Marco, Napoli, Alessandra, Roux-Biejat, Paulina, De Palma, Clara, Moscheni, Claudia, Catalani, Elisabetta, Zecchini, Silvia, Conte, Vincenzo, Giovarelli, Matteo, Caccia, Sonia, Procacci, Patrizia, Cervia, Davide, Clementi, Emilio, Perrotta, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226741/
https://www.ncbi.nlm.nih.gov/pubmed/32244541
http://dx.doi.org/10.3390/cells9040848

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