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The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson’s Disease
MicroRNAs (miRNAs) are small double-stranded RNAs that exert a fine-tuning sequence-specific regulation of cell transcriptome. While one unique miRNA regulates hundreds of mRNAs, each mRNA molecule is commonly regulated by various miRNAs that bind to complementary sequences at 3’-untranslated region...
Autores principales: | Titze-de-Almeida, Simoneide S., Soto-Sánchez, Cristina, Fernandez, Eduardo, Koprich, James B., Brotchie, Jonathan M., Titze-de-Almeida, Ricardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226753/ https://www.ncbi.nlm.nih.gov/pubmed/32244357 http://dx.doi.org/10.3390/cells9040841 |
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