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Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity

Obtaining sufficient numbers of functional natural killer (NK) cells is crucial for the success of NK-cell-based adoptive immunotherapies. While expansion from peripheral blood (PB) is the current method of choice, ex vivo generation of NK cells from hematopoietic stem and progenitor cells (HSCs) ma...

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Detalles Bibliográficos
Autores principales:	Oberoi, Pranav, Kamenjarin, Kathrina, Villena Ossa, Jose Francisco, Uherek, Barbara, Bönig, Halvard, Wels, Winfried S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226771/ https://www.ncbi.nlm.nih.gov/pubmed/32230942 http://dx.doi.org/10.3390/cells9040811

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