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Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining

Technical improvements in clinical radiotherapy for maximizing cytotoxicity to the tumor while limiting negative impact on co-irradiated healthy tissues include the increasing use of particle therapy (e.g., proton therapy) worldwide. Yet potential differences in the biology of DNA damage induction a...

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Detalles Bibliográficos
Autores principales:	Szymonowicz, Klaudia, Krysztofiak, Adam, van der Linden, Jansje, Kern, Ajvar, Deycmar, Simon, Oeck, Sebastian, Squire, Anthony, Koska, Benjamin, Hlouschek, Julian, Vüllings, Melanie, Neander, Christian, Siveke, Jens T., Matschke, Johann, Pruschy, Martin, Timmermann, Beate, Jendrossek, Verena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226794/ https://www.ncbi.nlm.nih.gov/pubmed/32260562 http://dx.doi.org/10.3390/cells9040889

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