CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy

The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic target. CCN2/CTGF is a profibrotic matricellular prot...

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Detalles Bibliográficos
Autores principales: Resovi, Andrea, Borsotti, Patrizia, Ceruti, Tommaso, Passoni, Alice, Zucchetti, Massimo, Berndt, Alexander, Riser, Bruce L., Taraboletti, Giulia, Belotti, Dorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226963/
https://www.ncbi.nlm.nih.gov/pubmed/32294968
http://dx.doi.org/10.3390/cells9040952

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