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Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model

To unravel the failure of remyelination in multiple sclerosis (MS) and to test promising remyelinating treatments, suitable animal models like the well-established cuprizone model are required. However, this model is only standardized in young mice. This does not represent the typical age of MS pati...

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Detalles Bibliográficos
Autores principales:	Gingele, Stefan, Henkel, Florian, Heckers, Sandra, Moellenkamp, Thiemo M., Hümmert, Martin W., Skripuletz, Thomas, Stangel, Martin, Gudi, Viktoria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226973/ https://www.ncbi.nlm.nih.gov/pubmed/32290524 http://dx.doi.org/10.3390/cells9040945

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