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Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the opportunity to use human brain-specific cells to es...
Autores principales: | Di Marco, Annalise, Vignone, Domenico, Gonzalez Paz, Odalys, Fini, Ivan, Battista, Maria Rosaria, Cellucci, Antonella, Bracacel, Elena, Auciello, Giulio, Veneziano, Maria, Khetarpal, Vinod, Rose, Mark, Rosa, Alessandro, Gloaguen, Isabelle, Monteagudo, Edith, Herbst, Todd, Dominguez, Celia, Muñoz-Sanjuán, Ignacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226989/ https://www.ncbi.nlm.nih.gov/pubmed/32316221 http://dx.doi.org/10.3390/cells9040994 |
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