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Modification of i-GONAD Suitable for Production of Genome-Edited C57BL/6 Inbred Mouse Strain
Improved genome editing via oviductal nucleic acid delivery (i-GONAD) is a novel method for producing genome-edited mice in the absence of ex vivo handling of zygotes. i-GONAD involves the intraoviductal injection of clustered regularly interspaced short palindromic repeats (CRISPR) ribonucleoprotei...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226992/ https://www.ncbi.nlm.nih.gov/pubmed/32295056 http://dx.doi.org/10.3390/cells9040957 |