Modification of i-GONAD Suitable for Production of Genome-Edited C57BL/6 Inbred Mouse Strain

Improved genome editing via oviductal nucleic acid delivery (i-GONAD) is a novel method for producing genome-edited mice in the absence of ex vivo handling of zygotes. i-GONAD involves the intraoviductal injection of clustered regularly interspaced short palindromic repeats (CRISPR) ribonucleoprotei...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yukari, Aoshima, Takuya, Ito, Ryota, Shinmura, Ryota, Ohtsuka, Masato, Akasaka, Eri, Sato, Masahiro, Takabayashi, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226992/
https://www.ncbi.nlm.nih.gov/pubmed/32295056
http://dx.doi.org/10.3390/cells9040957

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