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Electro-Osmotic Vortices Promote the Capture of Folded Proteins by PlyAB Nanopores
[Image: see text] Biological nanopores are emerging as powerful tools for single-molecule analysis and sequencing. Here, we engineered the two-component pleurotolysin (PlyAB) toxin to assemble into 7.2 × 10.5 nm cylindrical nanopores with a low level of electrical noise in lipid bilayers, and we add...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227020/ https://www.ncbi.nlm.nih.gov/pubmed/32271587 http://dx.doi.org/10.1021/acs.nanolett.0c00877 |