Fucose-Galactose Polymers Inhibit Cholera Toxin Binding to Fucosylated Structures and Galactose-Dependent Intoxication of Human Enteroids

[Image: see text] A promising strategy to limit cholera severity involves blockers mimicking the canonical cholera toxin ligand (CT) ganglioside GM1. However, to date the efficacies of most of these blockers have been evaluated in noncellular systems that lack ligands other than GM1. Importantly, th...

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Detalles Bibliográficos
Autores principales: Cervin, Jakob, Boucher, Andrew, Youn, Gyusaang, Björklund, Per, Wallenius, Ville, Mottram, Lynda, Sampson, Nicole S., Yrlid, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227030/
https://www.ncbi.nlm.nih.gov/pubmed/32134631
http://dx.doi.org/10.1021/acsinfecdis.0c00009

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