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A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use

BACKGROUND: Isotretinoin (ISO) is a synthetic vitamin A derivative which has been used for treatment-resistant acne vulgaris. Although most musculoskeletal side effects of ISO are common, including myalgia, arthralgia, and back pain, sacroiliitis is one of the uncommon side effects. ISO-induced sacr...

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Autores principales: Mülkoğlu, Cevriye, Nacır, Barış
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227041/
https://www.ncbi.nlm.nih.gov/pubmed/32410688
http://dx.doi.org/10.1186/s12891-020-03290-6
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author Mülkoğlu, Cevriye
Nacır, Barış
author_facet Mülkoğlu, Cevriye
Nacır, Barış
author_sort Mülkoğlu, Cevriye
collection PubMed
description BACKGROUND: Isotretinoin (ISO) is a synthetic vitamin A derivative which has been used for treatment-resistant acne vulgaris. Although most musculoskeletal side effects of ISO are common, including myalgia, arthralgia, and back pain, sacroiliitis is one of the uncommon side effects. ISO-induced sacroiliitis usually completely resolves within a few months by the cessation of the drug. CASE PRESENTATION: In this paper, we present a 26-year-old female patient with chronic sacroiliitis that was probably induced by ISO and not resolved by the discontinuation of the drug. CONCLUSION: In this patient, sacroiliitis was overlooked for three years. Therefore, ISO usage should be considered in the differential diagnosis of sacroiliitis and low back pain.
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spelling pubmed-72270412020-05-27 A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use Mülkoğlu, Cevriye Nacır, Barış BMC Musculoskelet Disord Case Report BACKGROUND: Isotretinoin (ISO) is a synthetic vitamin A derivative which has been used for treatment-resistant acne vulgaris. Although most musculoskeletal side effects of ISO are common, including myalgia, arthralgia, and back pain, sacroiliitis is one of the uncommon side effects. ISO-induced sacroiliitis usually completely resolves within a few months by the cessation of the drug. CASE PRESENTATION: In this paper, we present a 26-year-old female patient with chronic sacroiliitis that was probably induced by ISO and not resolved by the discontinuation of the drug. CONCLUSION: In this patient, sacroiliitis was overlooked for three years. Therefore, ISO usage should be considered in the differential diagnosis of sacroiliitis and low back pain. BioMed Central 2020-05-14 /pmc/articles/PMC7227041/ /pubmed/32410688 http://dx.doi.org/10.1186/s12891-020-03290-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Mülkoğlu, Cevriye
Nacır, Barış
A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title_full A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title_fullStr A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title_full_unstemmed A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title_short A patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
title_sort patient with chronic sacroiliitis undiagnosed for three years after isotretinoin use
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227041/
https://www.ncbi.nlm.nih.gov/pubmed/32410688
http://dx.doi.org/10.1186/s12891-020-03290-6
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