Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current

[Image: see text] Macrocyclic cucurbit[n]uril (CB[n]) molecules have triggered renewed interest because of their outstanding capabilities as host molecules to selectively interact with a wide range of small guest molecules. Here, CB[7]-based host–guest interactions were investigated for a guest-modi...

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Autores principales: Ai, Qiushuang, Jin, Lunqiang, Gong, Zhengjie, Liang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227043/
https://www.ncbi.nlm.nih.gov/pubmed/32426616
http://dx.doi.org/10.1021/acsomega.0c01077
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author Ai, Qiushuang
Jin, Lunqiang
Gong, Zhengjie
Liang, Feng
author_facet Ai, Qiushuang
Jin, Lunqiang
Gong, Zhengjie
Liang, Feng
author_sort Ai, Qiushuang
collection PubMed
description [Image: see text] Macrocyclic cucurbit[n]uril (CB[n]) molecules have triggered renewed interest because of their outstanding capabilities as host molecules to selectively interact with a wide range of small guest molecules. Here, CB[7]-based host–guest interactions were investigated for a guest-modified nanoelectrode by monitoring the electrochemical current. A ferrocene (Fc)-terminated molecule immobilized on a gold nanoelectrode (GNE) showed suitable affinity with CB[7] when the effective exposing area of the GNE was between 5.3 and 12 μm(2) and the bias applied on the GNE was −500 mV. Monitoring the dynamics of nanoparticles (NPs) on a nanoelectrode provides new insights into the host–guest interactions at molecular interfaces.
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spelling pubmed-72270432020-05-18 Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current Ai, Qiushuang Jin, Lunqiang Gong, Zhengjie Liang, Feng ACS Omega [Image: see text] Macrocyclic cucurbit[n]uril (CB[n]) molecules have triggered renewed interest because of their outstanding capabilities as host molecules to selectively interact with a wide range of small guest molecules. Here, CB[7]-based host–guest interactions were investigated for a guest-modified nanoelectrode by monitoring the electrochemical current. A ferrocene (Fc)-terminated molecule immobilized on a gold nanoelectrode (GNE) showed suitable affinity with CB[7] when the effective exposing area of the GNE was between 5.3 and 12 μm(2) and the bias applied on the GNE was −500 mV. Monitoring the dynamics of nanoparticles (NPs) on a nanoelectrode provides new insights into the host–guest interactions at molecular interfaces. American Chemical Society 2020-04-30 /pmc/articles/PMC7227043/ /pubmed/32426616 http://dx.doi.org/10.1021/acsomega.0c01077 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Ai, Qiushuang
Jin, Lunqiang
Gong, Zhengjie
Liang, Feng
Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title_full Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title_fullStr Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title_full_unstemmed Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title_short Observing Host–Guest Interactions at Molecular Interfaces by Monitoring the Electrochemical Current
title_sort observing host–guest interactions at molecular interfaces by monitoring the electrochemical current
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227043/
https://www.ncbi.nlm.nih.gov/pubmed/32426616
http://dx.doi.org/10.1021/acsomega.0c01077
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AT jinlunqiang observinghostguestinteractionsatmolecularinterfacesbymonitoringtheelectrochemicalcurrent
AT gongzhengjie observinghostguestinteractionsatmolecularinterfacesbymonitoringtheelectrochemicalcurrent
AT liangfeng observinghostguestinteractionsatmolecularinterfacesbymonitoringtheelectrochemicalcurrent

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