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Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality

BACKGROUND: Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percuta...

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Autores principales: Taylor, Lee K., Nelson, Michael A., Gale, Marianne, Trevena, Judy, Brieger, David B., Winch, Scott, Cretikos, Michelle A., Newman, Leah A., Phung, Hai N., Faddy, Steven C., Kelly, Paul M., Chant, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227061/
https://www.ncbi.nlm.nih.gov/pubmed/32408860
http://dx.doi.org/10.1186/s12872-020-01487-0
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author Taylor, Lee K.
Nelson, Michael A.
Gale, Marianne
Trevena, Judy
Brieger, David B.
Winch, Scott
Cretikos, Michelle A.
Newman, Leah A.
Phung, Hai N.
Faddy, Steven C.
Kelly, Paul M.
Chant, Kerry
author_facet Taylor, Lee K.
Nelson, Michael A.
Gale, Marianne
Trevena, Judy
Brieger, David B.
Winch, Scott
Cretikos, Michelle A.
Newman, Leah A.
Phung, Hai N.
Faddy, Steven C.
Kelly, Paul M.
Chant, Kerry
author_sort Taylor, Lee K.
collection PubMed
description BACKGROUND: Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Graft (CABG) in New South Wales (NSW) and the Australian Capital Territory (ACT), Australia. METHODS: This was an observational cohort study using linked population health data. We used linked records of NSW and the ACT hospitalisations and the Australian Government Medicare Benefits Schedule (MBS) for persons aged 35 and over hospitalised with STEMI in the period 1 July 2010 to 30 June 2014. Survival analysis was used to determine the time between STEMI admission and angiography, PCI and CABG, with a competing risk of death without cardiac procedure. RESULTS: Of 13,117 STEMI hospitalisations, 71% were among males; 55% were 65-plus years; 64% lived in major cities, and 2.6% were Aboriginal people. STEMI hospitalisation occurred at a younger age in males than females. Angiography and PCI rates decreased with age: angiography 69% vs 42% and PCI 60% vs 34% on day 0 for ages 35-44 and 75-plus respectively. Lower angiography and PCI rates and higher CABG rates were observed outside major cities. Aboriginal people with STEMI were younger and more likely to live outside a major city. Angiography, PCI and CABG rates were similar for Aboriginal and non-Aboriginal people of the same age and remoteness area. CONCLUSIONS: There is a need to improve access to definitive revascularisation for STEMI among appropriately selected older patients and in regional areas. Aboriginal people with STEMI, as a population, are disproportionately affected by access to definitive revascularisation outside major cities. Improving access to timely definitive revascularisation in regional areas may assist in closing the gap in cardiovascular outcomes between Aboriginal and non-Aboriginal people.
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spelling pubmed-72270612020-05-27 Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality Taylor, Lee K. Nelson, Michael A. Gale, Marianne Trevena, Judy Brieger, David B. Winch, Scott Cretikos, Michelle A. Newman, Leah A. Phung, Hai N. Faddy, Steven C. Kelly, Paul M. Chant, Kerry BMC Cardiovasc Disord Research Article BACKGROUND: Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Graft (CABG) in New South Wales (NSW) and the Australian Capital Territory (ACT), Australia. METHODS: This was an observational cohort study using linked population health data. We used linked records of NSW and the ACT hospitalisations and the Australian Government Medicare Benefits Schedule (MBS) for persons aged 35 and over hospitalised with STEMI in the period 1 July 2010 to 30 June 2014. Survival analysis was used to determine the time between STEMI admission and angiography, PCI and CABG, with a competing risk of death without cardiac procedure. RESULTS: Of 13,117 STEMI hospitalisations, 71% were among males; 55% were 65-plus years; 64% lived in major cities, and 2.6% were Aboriginal people. STEMI hospitalisation occurred at a younger age in males than females. Angiography and PCI rates decreased with age: angiography 69% vs 42% and PCI 60% vs 34% on day 0 for ages 35-44 and 75-plus respectively. Lower angiography and PCI rates and higher CABG rates were observed outside major cities. Aboriginal people with STEMI were younger and more likely to live outside a major city. Angiography, PCI and CABG rates were similar for Aboriginal and non-Aboriginal people of the same age and remoteness area. CONCLUSIONS: There is a need to improve access to definitive revascularisation for STEMI among appropriately selected older patients and in regional areas. Aboriginal people with STEMI, as a population, are disproportionately affected by access to definitive revascularisation outside major cities. Improving access to timely definitive revascularisation in regional areas may assist in closing the gap in cardiovascular outcomes between Aboriginal and non-Aboriginal people. BioMed Central 2020-05-14 /pmc/articles/PMC7227061/ /pubmed/32408860 http://dx.doi.org/10.1186/s12872-020-01487-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Taylor, Lee K.
Nelson, Michael A.
Gale, Marianne
Trevena, Judy
Brieger, David B.
Winch, Scott
Cretikos, Michelle A.
Newman, Leah A.
Phung, Hai N.
Faddy, Steven C.
Kelly, Paul M.
Chant, Kerry
Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title_full Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title_fullStr Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title_full_unstemmed Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title_short Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality
title_sort cardiac procedures in st-segment-elevation myocardial infarction - the influence of age, geography and aboriginality
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227061/
https://www.ncbi.nlm.nih.gov/pubmed/32408860
http://dx.doi.org/10.1186/s12872-020-01487-0
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