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Detecting transcriptomic structural variants in heterogeneous contexts via the Multiple Compatible Arrangements Problem

BACKGROUND: Transcriptomic structural variants (TSVs)—large-scale transcriptome sequence change due to structural variation - are common in cancer. TSV detection from high-throughput sequencing data is a computationally challenging problem. Among all the confounding factors, sample heterogeneity, wh...

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Detalles Bibliográficos
Autores principales: Qiu, Yutong, Ma, Cong, Xie, Han, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227063/
https://www.ncbi.nlm.nih.gov/pubmed/32467720
http://dx.doi.org/10.1186/s13015-020-00170-5

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