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Detecting transcriptomic structural variants in heterogeneous contexts via the Multiple Compatible Arrangements Problem
BACKGROUND: Transcriptomic structural variants (TSVs)—large-scale transcriptome sequence change due to structural variation - are common in cancer. TSV detection from high-throughput sequencing data is a computationally challenging problem. Among all the confounding factors, sample heterogeneity, wh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227063/ https://www.ncbi.nlm.nih.gov/pubmed/32467720 http://dx.doi.org/10.1186/s13015-020-00170-5 |