Interpretation of within-group change in randomised trials

In medicine, it is common to observe improvement after intervention, at least partly because patients present for care in extremis and would have improved without intervention. Controlling for this counterfactual explanation for improvement is the principle reason to conduct a trial in which patient...

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Autor principal: Kypri, Kypros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227072/
https://www.ncbi.nlm.nih.gov/pubmed/32410596
http://dx.doi.org/10.1186/s12888-020-02641-w
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author Kypri, Kypros
author_facet Kypri, Kypros
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description In medicine, it is common to observe improvement after intervention, at least partly because patients present for care in extremis and would have improved without intervention. Controlling for this counterfactual explanation for improvement is the principle reason to conduct a trial in which patients are randomised to treatment or a control group. Accordingly, it is not reasonable to infer that both interventions are effective when the groups show similar improvements in outcome.
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spelling pubmed-72270722020-05-27 Interpretation of within-group change in randomised trials Kypri, Kypros BMC Psychiatry Correspondence In medicine, it is common to observe improvement after intervention, at least partly because patients present for care in extremis and would have improved without intervention. Controlling for this counterfactual explanation for improvement is the principle reason to conduct a trial in which patients are randomised to treatment or a control group. Accordingly, it is not reasonable to infer that both interventions are effective when the groups show similar improvements in outcome. BioMed Central 2020-05-14 /pmc/articles/PMC7227072/ /pubmed/32410596 http://dx.doi.org/10.1186/s12888-020-02641-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Correspondence
Kypri, Kypros
Interpretation of within-group change in randomised trials
title Interpretation of within-group change in randomised trials
title_full Interpretation of within-group change in randomised trials
title_fullStr Interpretation of within-group change in randomised trials
title_full_unstemmed Interpretation of within-group change in randomised trials
title_short Interpretation of within-group change in randomised trials
title_sort interpretation of within-group change in randomised trials
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227072/
https://www.ncbi.nlm.nih.gov/pubmed/32410596
http://dx.doi.org/10.1186/s12888-020-02641-w
work_keys_str_mv AT kyprikypros interpretationofwithingroupchangeinrandomisedtrials

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