Quercetin with the potential effect on allergic diseases

Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releas...

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Autores principales: Jafarinia, Morteza, Sadat Hosseini, Mahnaz, kasiri, Neda, Fazel, Niloofar, Fathi, Farshid, Ganjalikhani Hakemi, Mazdak, Eskandari, Nahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227109/
https://www.ncbi.nlm.nih.gov/pubmed/32467711
http://dx.doi.org/10.1186/s13223-020-00434-0
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author Jafarinia, Morteza
Sadat Hosseini, Mahnaz
kasiri, Neda
Fazel, Niloofar
Fathi, Farshid
Ganjalikhani Hakemi, Mazdak
Eskandari, Nahid
author_facet Jafarinia, Morteza
Sadat Hosseini, Mahnaz
kasiri, Neda
Fazel, Niloofar
Fathi, Farshid
Ganjalikhani Hakemi, Mazdak
Eskandari, Nahid
author_sort Jafarinia, Morteza
collection PubMed
description Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD).
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spelling pubmed-72271092020-05-27 Quercetin with the potential effect on allergic diseases Jafarinia, Morteza Sadat Hosseini, Mahnaz kasiri, Neda Fazel, Niloofar Fathi, Farshid Ganjalikhani Hakemi, Mazdak Eskandari, Nahid Allergy Asthma Clin Immunol Review Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD). BioMed Central 2020-05-14 /pmc/articles/PMC7227109/ /pubmed/32467711 http://dx.doi.org/10.1186/s13223-020-00434-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Jafarinia, Morteza
Sadat Hosseini, Mahnaz
kasiri, Neda
Fazel, Niloofar
Fathi, Farshid
Ganjalikhani Hakemi, Mazdak
Eskandari, Nahid
Quercetin with the potential effect on allergic diseases
title Quercetin with the potential effect on allergic diseases
title_full Quercetin with the potential effect on allergic diseases
title_fullStr Quercetin with the potential effect on allergic diseases
title_full_unstemmed Quercetin with the potential effect on allergic diseases
title_short Quercetin with the potential effect on allergic diseases
title_sort quercetin with the potential effect on allergic diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227109/
https://www.ncbi.nlm.nih.gov/pubmed/32467711
http://dx.doi.org/10.1186/s13223-020-00434-0
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