Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain

BACKGROUND: Chemokine receptor CXCR4 has been found to be associated with spinal neuron and glial cell activation during bone cancer pain. However, the underlying mechanism remains unknown. Furthermore, the RhoA/ROCK2 pathway serves as a downstream pathway activated by CXCR4 during bone cancer pain....

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Detalles Bibliográficos
Autores principales: Xu, Heng, Peng, Chong, Chen, Xue-Tai, Yao, Ying-Ying, Chen, Li-Ping, Yin, Qin, Shen, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227150/
https://www.ncbi.nlm.nih.gov/pubmed/32349612
http://dx.doi.org/10.1177/1744806920919568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227150/
https://www.ncbi.nlm.nih.gov/pubmed/32349612
http://dx.doi.org/10.1177/1744806920919568

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