Cargando…

Wnt/β-catenin signaling regulates brain-derived neurotrophic factor release from spinal microglia to mediate HIV(1) gp120-induced neuropathic pain

HIV-associated neuropathic pain (HNP) is a common complication for AIDS patients. The pathological mechanism governing HNP has not been elucidated, and HNP has no effective analgesic treatment. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic factor family related to the plas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Xinxin, Tao, Lei, Zhao, Mengru, Wu, Shengjun, Obeng, Enoch, Wang, Dan, Zhang, Wenping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227158/ https://www.ncbi.nlm.nih.gov/pubmed/32354292 http://dx.doi.org/10.1177/1744806920922100

Ejemplares similares

Glial TNFα in the spinal cord regulates neuropathic pain induced by HIV gp120 application in rats
por: Zheng, Wenwen, et al.
Publicado: (2011)

ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain
por: Chu, Jiachen, et al.
Publicado: (2023)

Microglia in the spinal cord and neuropathic pain
por: Tsuda, Makoto
Publicado: (2015)

HSV vector-mediated GAD67 suppresses neuropathic pain induced by perineural HIV gp120 in rats through inhibition of ROS and Wnt5a
por: Kanda, Hirotsugu, et al.
Publicado: (2016)

GPR34 in spinal microglia exacerbates neuropathic pain in mice
por: Sayo, Akira, et al.
Publicado: (2019)

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
por: Navia-Pelaez, Juliana M., et al.
Publicado: (2021)

Curcumin Protects Microglia and Primary Rat Cortical Neurons against HIV-1 gp120-Mediated Inflammation and Apoptosis
por: Guo, Luyan, et al.
Publicado: (2013)

Morphine and HIV-1 gp120 cooperatively promote pathogenesis in the spinal pain neural circuit
por: Shi, Yuqiang, et al.
Publicado: (2019)

Role of Microglia and Astrocytes in Spinal Cord Injury Induced Neuropathic Pain
por: Miranpuri, Gurwattan S., et al.
Publicado: (2021)

Effect of naringin on gp120-induced injury mediated by P2X(7) receptors in rat primary cultured microglia
por: Chen, Qiang, et al.
Publicado: (2017)

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice
por: Moss, Emaya M., et al.
Publicado: (2023)

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins
por: Herschhorn, Alon, et al.
Publicado: (2016)

Eliciting neutralizing antibodies with gp120 outer domain
por: Qin, Y, et al.
Publicado: (2012)

Internalization and Axonal Transport of the HIV Glycoprotein gp120
por: Berth, Sarah, et al.
Publicado: (2015)

CK1ε and p120‐catenin control Ror2 function in noncanonical Wnt signaling
por: Curto, Josué, et al.
Publicado: (2018)

Mediators of Neuropathic Pain; Focus on Spinal Microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt Ligands, and Interleukin 1β
por: Boakye, Paul A., et al.
Publicado: (2021)

Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity
por: Drummer, Heidi E., et al.
Publicado: (2013)

Microglia: sculptors of neuropathic pain?
por: Ward, Harry, et al.
Publicado: (2020)

Role of Microglia in Neuropathic Pain
por: Karavis, Miltiades Y, et al.
Publicado: (2023)

IL-10 mediated by herpes simplex virus vector reduces neuropathic pain induced by HIV gp120 combined with ddC in rats
por: Zheng, Wenwen, et al.
Publicado: (2014)

HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells
por: Marone, Giancarlo, et al.
Publicado: (2020)

Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15
por: McKee, Hayley J, et al.
Publicado: (2004)

Development of Protein- and Peptide-Based HIV Entry Inhibitors Targeting gp120 or gp41
por: Pu, Jing, et al.
Publicado: (2019)

Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface
por: Torrents de la Peña, Alba, et al.
Publicado: (2021)

NMR spectroscopy of HIV-1 gp120 outer domain
por: Sastry, M, et al.
Publicado: (2012)

Behavioral Evidence for a Tau and HIV-gp120 Interaction
por: Vijayan, Murali, et al.
Publicado: (2022)

Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides
por: Kassler, Kristin, et al.
Publicado: (2011)

Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41
por: Sanders, Rogier W, et al.
Publicado: (2004)

The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model
por: Zhang, Ye, et al.
Publicado: (2021)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
por: Visciano, Maria Luisa, et al.
Publicado: (2008)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Deletion of the Highly Conserved N-Glycan at Asn260 of HIV-1 gp120 Affects Folding and Lysosomal Degradation of gp120, and Results in Loss of Viral Infectivity
por: Mathys, Leen, et al.
Publicado: (2014)

Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector
por: Khattar, Sunil K., et al.
Publicado: (2013)

HLA-C increases HIV-1 infectivity and is associated with gp120
por: Matucci, Andrea, et al.
Publicado: (2008)

The C5 region of HIV-1 gp120 binds specific
por: Dalgleish, A, et al.
Publicado: (2006)

Nitric oxide protects against HIV gp120 endothelial injury
por: Fiorucci, S, et al.
Publicado: (2010)

Structural Plasticity and Conformational Transitions of HIV Envelope Glycoprotein gp120
por: Korkut, Anil, et al.
Publicado: (2012)

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate
por: Stansell, Elizabeth, et al.
Publicado: (2015)

Helix-A peptide prevents gp120-mediated neuronal loss
por: Avdoshina, Valeria, et al.
Publicado: (2019)

Amyloidogenic, neuroinflammatory and memory dysfunction effects of HIV-1 gp120
por: Lee, Young-Jung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fgi4ahqpt1og8h2hq7uocg98dp