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Clostridium Perfringens in Gas Gangrene: Still a Smoked Gun!

Gas gangrene (GG) remains a life-threatening and deadly disease. Early recognition together with daily surgical debridement remains the mainstay of therapy. We sought to describe a fatal case of necrotizing soft tissue infection, which was a gas gagrene in this case. This case was remarkable as two...

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Detalles Bibliográficos
Autores principales: Preseau, Thierry, Deviendt, Jacques, Duttman, Ruth, Attou, Rachid, Franck, Diane, Claeys, Ruben, Honoré, Patrick M., Bels, David De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227166/
https://www.ncbi.nlm.nih.gov/pubmed/32435613
http://dx.doi.org/10.2478/jtim-2020-0009
Descripción
Sumario:Gas gangrene (GG) remains a life-threatening and deadly disease. Early recognition together with daily surgical debridement remains the mainstay of therapy. We sought to describe a fatal case of necrotizing soft tissue infection, which was a gas gagrene in this case. This case was remarkable as two main sites were infected simultaneously in geographical zones very far from each other making dissemination between both sites almost impossible. The other particularity was the fact that the infection was caused at the same time by four different bacteria that is atypical in GG similar to that in streptoccocal necrotizing fasciitis where one bacteria is the causative agent (Clostridium perfringens for GG and group A streptococcus for necrotizing fasciitis).