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Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation

The study explores the role of neddylation in early trophoblast development and its alteration during the pathogenesis of recurrent spontaneous abortion (RSA). Immunofluorescence and western blot were conducted to evaluate the expression pattern of NEDD8 protein in the first-trimester placentas of h...

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Detalles Bibliográficos
Autores principales:	Sun, Xiaohe, Tong, Xiaomei, Hao, Yanqing, Li, Chao, Zhang, Yinli, Pan, Yibin, Dai, Yongdong, Liu, Liu, Zhang, Tai, Zhang, Songying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227182/ https://www.ncbi.nlm.nih.gov/pubmed/32186736 http://dx.doi.org/10.1093/molehr/gaaa021

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