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Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study

BACKGROUND: For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years. METHODS: Between 01/09 and 12/18, a total of 95 patients with refractory overa...

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Autores principales: Schönburg, Sandra, Bukethal, Tobias, Fornara, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227205/
https://www.ncbi.nlm.nih.gov/pubmed/32410612
http://dx.doi.org/10.1186/s12894-020-00621-6
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author Schönburg, Sandra
Bukethal, Tobias
Fornara, Paolo
author_facet Schönburg, Sandra
Bukethal, Tobias
Fornara, Paolo
author_sort Schönburg, Sandra
collection PubMed
description BACKGROUND: For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years. METHODS: Between 01/09 and 12/18, a total of 95 patients with refractory overactive bladder (OAB) or chronic non-obstructive urinary retention underwent SNM testing at our department. In the overall sample, 20 patients were aged 70 years or older (21%, group B), and 75 patients were under 70 years old (79%, group A). The mean follow-up period was 50.2 ± 36.2 months. Pre-, peri- and postoperative parameters were compared between the two groups. Statistical analysis was carried out with SPSS 25.0 (p < 0.05). RESULTS: The mean patient age was 53 ± 16 (17–76) years. The indications for SNM testing were OAB and retention in 51 and 49% of patients, respectively. A total of 56 patients (59%) [8 patients (40%) in group B, 48 patients (64%) in group A] had more than 50% improvement in the context of the test (stage 1), such that a permanent neuromodulator (stage 2) was implanted. A total of 14 patients, all under 70 years old except for one older female, needed to undergo revision due to defects or infection. Overall, the success rate was 58.3% for OAB and 59.6% for urinary retention. The success rates and complications in our patient group were independent of age and geriatric assessment. CONCLUSION: SNM can also be successfully implemented in older patients.
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spelling pubmed-72272052020-05-27 Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study Schönburg, Sandra Bukethal, Tobias Fornara, Paolo BMC Urol Research Article BACKGROUND: For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years. METHODS: Between 01/09 and 12/18, a total of 95 patients with refractory overactive bladder (OAB) or chronic non-obstructive urinary retention underwent SNM testing at our department. In the overall sample, 20 patients were aged 70 years or older (21%, group B), and 75 patients were under 70 years old (79%, group A). The mean follow-up period was 50.2 ± 36.2 months. Pre-, peri- and postoperative parameters were compared between the two groups. Statistical analysis was carried out with SPSS 25.0 (p < 0.05). RESULTS: The mean patient age was 53 ± 16 (17–76) years. The indications for SNM testing were OAB and retention in 51 and 49% of patients, respectively. A total of 56 patients (59%) [8 patients (40%) in group B, 48 patients (64%) in group A] had more than 50% improvement in the context of the test (stage 1), such that a permanent neuromodulator (stage 2) was implanted. A total of 14 patients, all under 70 years old except for one older female, needed to undergo revision due to defects or infection. Overall, the success rate was 58.3% for OAB and 59.6% for urinary retention. The success rates and complications in our patient group were independent of age and geriatric assessment. CONCLUSION: SNM can also be successfully implemented in older patients. BioMed Central 2020-05-14 /pmc/articles/PMC7227205/ /pubmed/32410612 http://dx.doi.org/10.1186/s12894-020-00621-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Schönburg, Sandra
Bukethal, Tobias
Fornara, Paolo
Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title_full Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title_fullStr Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title_full_unstemmed Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title_short Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study
title_sort does age alone negatively predict the outcome of sacral neuromodulation? a single-centre retrospective observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227205/
https://www.ncbi.nlm.nih.gov/pubmed/32410612
http://dx.doi.org/10.1186/s12894-020-00621-6
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