Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD(+)/NADH ratio

BACKGROUND: Non-alcoholic fatty liver disease is often associated with obesity, insulin resistance, dyslipidemia, and the metabolic syndrome in addition to mitochondrial dysfunction and nicotinamide adenine dinucleotide (NAD(+)) deficiency. The aim of this study was to investigate how inhibition of...

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Detalles Bibliográficos
Autores principales: Berge, Rolf K., Cacabelos, Daniel, Señarís, Rosa, Nordrehaug, Jan Erik, Nygård, Ottar, Skorve, Jon, Bjørndal, Bodil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227213/
https://www.ncbi.nlm.nih.gov/pubmed/32410680
http://dx.doi.org/10.1186/s12944-020-01271-1

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