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Spatiotemporal Mislocalization of Nuclear Membrane-Associated Proteins in γ-Irradiation-Induced Senescent Cells
Cellular senescence, induced by genotoxic or replication stress, is accompanied by defects in nuclear morphology and nuclear membrane-heterochromatin disruption. In this work, we analyzed cytological and molecular changes in the linker of nucleoskeleton and cytoskeleton (LINC) complex proteins in se...
Autores principales: | Alena, Svobodová Kovaříková, Eva, Bártová, Aleš, Kovařík, Emilie, Lukášová |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227243/ https://www.ncbi.nlm.nih.gov/pubmed/32316379 http://dx.doi.org/10.3390/cells9040999 |
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