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Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinoma

BACKGROUND: Overexpression of survivin plays a crucial role in tumorigenesis and correlates with poor prognosis in human malignancies. Thus, survivin has been proposed as an attractive target for new anti-tumor interventions. METHODS: A natural product library was used for natural compound screening...

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Detalles Bibliográficos
Autores principales:	Li, Ming, Gao, Feng, Yu, Xinfang, Zhao, Qing, Zhou, Li, Liu, Wenbin, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227341/ https://www.ncbi.nlm.nih.gov/pubmed/32410646 http://dx.doi.org/10.1186/s13046-020-01593-z

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