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Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice
BACKGROUND: Fractalkine (CX3CL1; FKN) is a chemokine expressed by neurons that mediates communication between neurons and microglia. By regulating microglial activity, CX3CL1 can mitigate the damaging effects of chronic microglial inflammation within the brain, a state that plays a major role in agi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227354/ https://www.ncbi.nlm.nih.gov/pubmed/32410624 http://dx.doi.org/10.1186/s12974-020-01828-y |