Effect of BMI on blood value of patients on HCG day with IUI treatment

BACKGROUND: This study aims to analyze the effect of the body mass index (BMI) on E(2), P and LH values in females who received intrauterine insemination (IUI) treatment on human chorionic gonadotropin (HCG) day. METHODS: A total of 2319 cycles of IUI-assisted pregnancy treatment were selected in our hospital. Based on the BMI, female infertility patients are divided into three groups: normal weight group, overweight and obese group. RESULTS: For patients with natural cycles and ≤ 35 years old, there were 440, 178 and 197 cases in the three groups, respectively. For patients with natural cycles and > 35 years old, there were 90, 83 and 81 cycles in the three groups, respectively. For patients with induced ovulation cycle and ≤ 35 years old, there were 425, 203 and 516 cases in the three groups, respectively. For patients with induced ovulation cycle and > 35 years old, there were 26, 26 and 54 cases in the three groups, respectively. CONCLUSION: When a patient is ≤35 years old, the BMI affects the E(2), LH and P values on the day of artificial insemination. However, the BMI is negatively correlated with E(2), LH and P in IUI on HCG day. After controlling for age and assisted pregnancy, the correlation analysis revealed that the BMI is negatively correlated with hormone E(2) and LH. The higher the BMI was, the lower the levels of hormones E(2), LH and P became. However, in the present study, the BMI did not significantly improve the clinical pregnancy rate of patients who received IUI.