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Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status

The effect of training status on post-exercise flow-mediated dilation (FMD) is not well characterized. We tested the hypothesis that the more trained the subjects, the lower the reduction in FMD after an acute bout of aerobic exercise. Forty-seven men (mean ± SD, age: 20.1 ± 1.2 years, body mass: 75...

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Autores principales: Kapilevich, L. V., Kologrivova, V. V., Zakharova, A. N., Mourot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227416/
https://www.ncbi.nlm.nih.gov/pubmed/32457640
http://dx.doi.org/10.3389/fphys.2020.00348
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author Kapilevich, L. V.
Kologrivova, V. V.
Zakharova, A. N.
Mourot, Laurent
author_facet Kapilevich, L. V.
Kologrivova, V. V.
Zakharova, A. N.
Mourot, Laurent
author_sort Kapilevich, L. V.
collection PubMed
description The effect of training status on post-exercise flow-mediated dilation (FMD) is not well characterized. We tested the hypothesis that the more trained the subjects, the lower the reduction in FMD after an acute bout of aerobic exercise. Forty-seven men (mean ± SD, age: 20.1 ± 1.2 years, body mass: 75.5 ± 5.1 kg, height 178.1 ± 5.4 cm) were divided into five groups with different training characteristics (sedentary, two different groups of active subjects, two different groups of well-trained subjects – runners and weightlifters). Brachial artery FMD (blood pressure cuff placed around the arm distal to the probe with the proximal border adjacent to the medial epicondyle; 5 min at a pressure of 220 mmHg) was assessed before and during 3 min immediately after a bout of cycling exercise at a relative intensity of 170 bpm [(physical work capacity (PWC(170))]. At baseline, a progressive increase in FMD was observed in the participants with the higher training status, if the training remained moderate. Indeed, FMD was reduced in runners and weightlifters compared to those who were moderately trained. After PWC(170), FMD did not significantly change in sedentary and highly trained runners, significantly increased in the two groups of active subjects but significantly decreased in highly trained weightlifters. These results showed that endothelium-dependent vasodilation evaluated using brachial FMD is maintained or improved following acute aerobic exercise in moderately trained participants, but not in well-trained participants, especially if they are engaged in resistance training.
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spelling pubmed-72274162020-05-25 Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status Kapilevich, L. V. Kologrivova, V. V. Zakharova, A. N. Mourot, Laurent Front Physiol Physiology The effect of training status on post-exercise flow-mediated dilation (FMD) is not well characterized. We tested the hypothesis that the more trained the subjects, the lower the reduction in FMD after an acute bout of aerobic exercise. Forty-seven men (mean ± SD, age: 20.1 ± 1.2 years, body mass: 75.5 ± 5.1 kg, height 178.1 ± 5.4 cm) were divided into five groups with different training characteristics (sedentary, two different groups of active subjects, two different groups of well-trained subjects – runners and weightlifters). Brachial artery FMD (blood pressure cuff placed around the arm distal to the probe with the proximal border adjacent to the medial epicondyle; 5 min at a pressure of 220 mmHg) was assessed before and during 3 min immediately after a bout of cycling exercise at a relative intensity of 170 bpm [(physical work capacity (PWC(170))]. At baseline, a progressive increase in FMD was observed in the participants with the higher training status, if the training remained moderate. Indeed, FMD was reduced in runners and weightlifters compared to those who were moderately trained. After PWC(170), FMD did not significantly change in sedentary and highly trained runners, significantly increased in the two groups of active subjects but significantly decreased in highly trained weightlifters. These results showed that endothelium-dependent vasodilation evaluated using brachial FMD is maintained or improved following acute aerobic exercise in moderately trained participants, but not in well-trained participants, especially if they are engaged in resistance training. Frontiers Media S.A. 2020-05-08 /pmc/articles/PMC7227416/ /pubmed/32457640 http://dx.doi.org/10.3389/fphys.2020.00348 Text en Copyright © 2020 Kapilevich, Kologrivova, Zakharova and Mourot. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Kapilevich, L. V.
Kologrivova, V. V.
Zakharova, A. N.
Mourot, Laurent
Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title_full Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title_fullStr Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title_full_unstemmed Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title_short Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
title_sort post-exercise endothelium-dependent vasodilation is dependent on training status
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227416/
https://www.ncbi.nlm.nih.gov/pubmed/32457640
http://dx.doi.org/10.3389/fphys.2020.00348
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