A randomized Phase I/II study to evaluate safety and reactogenicity of a heat-stable rotavirus vaccine in healthy adults followed by evaluation of the safety, reactogenicity, and immunogenicity in infants

Objectives: To assess the safety and reactogenicity of single oral dose of heat-stable rotavirus vaccine (HSRV) in healthy adults aged 18–45 years followed by assessment of safety, reactogenicity, and immunogenicity of three doses of HSRV in healthy infants aged 6–8 weeks at enrollment. Trial Design...

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Detalles Bibliográficos
Autores principales: Kanchan, Vibhu, Zaman, Khalequ, Aziz, Asma Binte, Zaman, Sheikh Farzana, Zaman, Farzana, Haque, Warda, Khanam, Mahbuba, Karim, Mohammad Mahbubul, Kale, Sachin, Ali, Syed Khalid, Goveia, Michelle G., Kaplan, Susan S., Gill, Davinder, Khan, Wasif Ali, Yunus, Mohammad, Singh, Ajitpal, Clemens, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227685/
https://www.ncbi.nlm.nih.gov/pubmed/31526218
http://dx.doi.org/10.1080/21645515.2019.1664239

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