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Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice
Inositol polyphosphate-4-phosphatase type II (INPP4B) is a dual-specificity phosphatase that acts as a tumor suppressor in multiple cancers. INPP4B dephosphorylates phospholipids at the 4th position of the inositol ring and inhibits AKT and PKC signaling by hydrolyzing of PI(3,4)P2 and PI(4,5)P2, re...
Autores principales: | Ceyhan, Yasemin, Zhang, Manqi, Guo, Jingtao, Sandoval, Carlos G., Vacher, Jean, Kaftanovskaya, Elena M., Agoulnik, Alexander I., Agoulnik, Irina U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228085/ https://www.ncbi.nlm.nih.gov/pubmed/32413098 http://dx.doi.org/10.1371/journal.pone.0233163 |
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