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Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study

BACKGROUND: Land-use changes in city fringes due to urbanization can lead to a reduction of greenspace that may reduce its associated health benefits. OBJECTIVES: We evaluated the association between changes in residential surrounding built-up land use and cardiometabolic risk factors in an urbanizi...

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Autores principales: Milà, Carles, Ranzani, Otavio, Sanchez, Margaux, Ambrós, Albert, Bhogadi, Santhi, Kinra, Sanjay, Kogevinas, Manolis, Dadvand, Payam, Tonne, Cathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228094/
https://www.ncbi.nlm.nih.gov/pubmed/32243204
http://dx.doi.org/10.1289/EHP5445
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author Milà, Carles
Ranzani, Otavio
Sanchez, Margaux
Ambrós, Albert
Bhogadi, Santhi
Kinra, Sanjay
Kogevinas, Manolis
Dadvand, Payam
Tonne, Cathryn
author_facet Milà, Carles
Ranzani, Otavio
Sanchez, Margaux
Ambrós, Albert
Bhogadi, Santhi
Kinra, Sanjay
Kogevinas, Manolis
Dadvand, Payam
Tonne, Cathryn
author_sort Milà, Carles
collection PubMed
description BACKGROUND: Land-use changes in city fringes due to urbanization can lead to a reduction of greenspace that may reduce its associated health benefits. OBJECTIVES: We evaluated the association between changes in residential surrounding built-up land use and cardiometabolic risk factors in an urbanizing peri-urban area of south India and explored the mediating roles of air pollution, physical activity, and stress in these associations. METHODS: We analyzed data on 6,039 adults from the third follow-up of the Andhra Pradesh Children and Parent Study (APCAPS) cohort (2010–2012). We generated trajectories of change in residential surrounding built-up land use (buffer areas) from 1995–2009 (stable, slow increase, fast increase) using remote sensing data and image classification methods. We estimated associations between built-up land use trajectories and natural log-transformed blood pressure, waist circumference, triglycerides, fasting glucose, and non–high-density lipoprotein (non-HDL) cholesterol using linear mixed models. We accounted for multiple mediators and the multilevel structure of the data in mediation analyses. RESULTS: We observed positive associations between a fast increase in built-up land use within [Formula: see text] of the home and all cardiometabolic risk factors. Compared with participants with stable trajectories, those with the largest increase in built-up land use had 1.5% (95% CI: 0.1, 2.9) higher systolic blood pressure, 2.4% (95% CI: 0.6, 4.3) higher diastolic blood pressure, 2.1% (95% CI: 0.5, 3.8) higher waist circumference, and 1.6% (95% CI: [Formula: see text] , 3.8) higher fasting glucose in fully adjusted models. Associations were positive, but not statistically significant, for triglycerides, fasting glucose, and non-HDL cholesterol. Physical activity and ambient particulate matter [Formula: see text] in aerodynamic diameter ([Formula: see text]) partially mediated the estimated associations. Associations between fast build-up and all cardiometabolic risk factors except non-HDL cholesterol were stronger in women than men. DISCUSSION: Increases in built-up land use surrounding residences were consistently associated with higher levels of cardiometabolic risk factors. Our findings support the need for better integration of health considerations in urban planning in rapidly urbanizing settings. https://doi.org/10.1289/EHP5445
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spelling pubmed-72280942020-05-18 Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study Milà, Carles Ranzani, Otavio Sanchez, Margaux Ambrós, Albert Bhogadi, Santhi Kinra, Sanjay Kogevinas, Manolis Dadvand, Payam Tonne, Cathryn Environ Health Perspect Research BACKGROUND: Land-use changes in city fringes due to urbanization can lead to a reduction of greenspace that may reduce its associated health benefits. OBJECTIVES: We evaluated the association between changes in residential surrounding built-up land use and cardiometabolic risk factors in an urbanizing peri-urban area of south India and explored the mediating roles of air pollution, physical activity, and stress in these associations. METHODS: We analyzed data on 6,039 adults from the third follow-up of the Andhra Pradesh Children and Parent Study (APCAPS) cohort (2010–2012). We generated trajectories of change in residential surrounding built-up land use (buffer areas) from 1995–2009 (stable, slow increase, fast increase) using remote sensing data and image classification methods. We estimated associations between built-up land use trajectories and natural log-transformed blood pressure, waist circumference, triglycerides, fasting glucose, and non–high-density lipoprotein (non-HDL) cholesterol using linear mixed models. We accounted for multiple mediators and the multilevel structure of the data in mediation analyses. RESULTS: We observed positive associations between a fast increase in built-up land use within [Formula: see text] of the home and all cardiometabolic risk factors. Compared with participants with stable trajectories, those with the largest increase in built-up land use had 1.5% (95% CI: 0.1, 2.9) higher systolic blood pressure, 2.4% (95% CI: 0.6, 4.3) higher diastolic blood pressure, 2.1% (95% CI: 0.5, 3.8) higher waist circumference, and 1.6% (95% CI: [Formula: see text] , 3.8) higher fasting glucose in fully adjusted models. Associations were positive, but not statistically significant, for triglycerides, fasting glucose, and non-HDL cholesterol. Physical activity and ambient particulate matter [Formula: see text] in aerodynamic diameter ([Formula: see text]) partially mediated the estimated associations. Associations between fast build-up and all cardiometabolic risk factors except non-HDL cholesterol were stronger in women than men. DISCUSSION: Increases in built-up land use surrounding residences were consistently associated with higher levels of cardiometabolic risk factors. Our findings support the need for better integration of health considerations in urban planning in rapidly urbanizing settings. https://doi.org/10.1289/EHP5445 Environmental Health Perspectives 2020-04-03 /pmc/articles/PMC7228094/ /pubmed/32243204 http://dx.doi.org/10.1289/EHP5445 Text en https://ehp.niehs.nih.gov/about-ehp/license EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. All content is public domain unless otherwise noted.
spellingShingle Research
Milà, Carles
Ranzani, Otavio
Sanchez, Margaux
Ambrós, Albert
Bhogadi, Santhi
Kinra, Sanjay
Kogevinas, Manolis
Dadvand, Payam
Tonne, Cathryn
Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title_full Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title_fullStr Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title_full_unstemmed Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title_short Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study
title_sort land-use change and cardiometabolic risk factors in an urbanizing area of south india: a population-based cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228094/
https://www.ncbi.nlm.nih.gov/pubmed/32243204
http://dx.doi.org/10.1289/EHP5445
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