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A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal

INTRODUCTION: Health facility-based records offer a rich source of information to understand trends and changes in malaria cases over time. This study is aimed at determining the changes in malaria occurrence over the last 28 years, from 1989 to 2016 in Dakar, Senegal. METHODS: Laboratory suspected...

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Autores principales: Diallo, Mamadou Alpha, Badiane, Aida Sadikh, Diongue, Khadim, Sakandé, Linda, Ndiaye, Mouhamadou, Seck, Mame Cheikh, Ndiaye, Daouda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228107/
https://www.ncbi.nlm.nih.gov/pubmed/32413069
http://dx.doi.org/10.1371/journal.pone.0231587
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author Diallo, Mamadou Alpha
Badiane, Aida Sadikh
Diongue, Khadim
Sakandé, Linda
Ndiaye, Mouhamadou
Seck, Mame Cheikh
Ndiaye, Daouda
author_facet Diallo, Mamadou Alpha
Badiane, Aida Sadikh
Diongue, Khadim
Sakandé, Linda
Ndiaye, Mouhamadou
Seck, Mame Cheikh
Ndiaye, Daouda
author_sort Diallo, Mamadou Alpha
collection PubMed
description INTRODUCTION: Health facility-based records offer a rich source of information to understand trends and changes in malaria cases over time. This study is aimed at determining the changes in malaria occurrence over the last 28 years, from 1989 to 2016 in Dakar, Senegal. METHODS: Laboratory suspected and confirmed malaria records from 1989 to 2016 were reviewed from the laboratory registers of the Laboratory of Parasitology and Mycology of Aristide Le Dantec Hospital. Interrupted time series (ITS) analysis was used to estimate the changes by comparing malaria cases post-intervention (2006–2016) with that of the pre-intervention (1989–2005) period. RESULTS: A total of 5,876 laboratory confirmed malaria cases were reported out of 29,852 tested cases, with total slide positivity rate (SPR) of 19.7%. Malaria case counts exhibited a fluctuating trend with major peaks occurring in the years 1995 and 2003 with SPR of 42.3% and 42.5%, respectively. Overall, a remarkable decline in the total number of laboratory confirmed malaria cases was observed over the last 28 years. P. falciparum was almost the only reported species, accounting for 99.98% of cases. The highest SPR was observed in the age group of under five years during the pre-intervention period while this shifted to the age group of 6–15 years old for the subsequent years. Two major malaria peak seasons were observed: one in September during the pre-intervention period and the other in November for the post-intervention period. The ITS analysis showed a dramatic decline of 83.6% in SPR following the scale-up of interventions in 2006. CONCLUSION: A remarkable decline in laboratory confirmed malaria cases in Dakar over 28 years was observed. The period of rapid decline in malaria SPR coincided with the scale-up in interventions beginning in 2006 with the introduction of ACTs, followed by the widespread introduction in 2008 of bed nets treated with insecticides. Robust surveillance data should be maintained in the context of malaria elimination efforts.
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spelling pubmed-72281072020-06-01 A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal Diallo, Mamadou Alpha Badiane, Aida Sadikh Diongue, Khadim Sakandé, Linda Ndiaye, Mouhamadou Seck, Mame Cheikh Ndiaye, Daouda PLoS One Research Article INTRODUCTION: Health facility-based records offer a rich source of information to understand trends and changes in malaria cases over time. This study is aimed at determining the changes in malaria occurrence over the last 28 years, from 1989 to 2016 in Dakar, Senegal. METHODS: Laboratory suspected and confirmed malaria records from 1989 to 2016 were reviewed from the laboratory registers of the Laboratory of Parasitology and Mycology of Aristide Le Dantec Hospital. Interrupted time series (ITS) analysis was used to estimate the changes by comparing malaria cases post-intervention (2006–2016) with that of the pre-intervention (1989–2005) period. RESULTS: A total of 5,876 laboratory confirmed malaria cases were reported out of 29,852 tested cases, with total slide positivity rate (SPR) of 19.7%. Malaria case counts exhibited a fluctuating trend with major peaks occurring in the years 1995 and 2003 with SPR of 42.3% and 42.5%, respectively. Overall, a remarkable decline in the total number of laboratory confirmed malaria cases was observed over the last 28 years. P. falciparum was almost the only reported species, accounting for 99.98% of cases. The highest SPR was observed in the age group of under five years during the pre-intervention period while this shifted to the age group of 6–15 years old for the subsequent years. Two major malaria peak seasons were observed: one in September during the pre-intervention period and the other in November for the post-intervention period. The ITS analysis showed a dramatic decline of 83.6% in SPR following the scale-up of interventions in 2006. CONCLUSION: A remarkable decline in laboratory confirmed malaria cases in Dakar over 28 years was observed. The period of rapid decline in malaria SPR coincided with the scale-up in interventions beginning in 2006 with the introduction of ACTs, followed by the widespread introduction in 2008 of bed nets treated with insecticides. Robust surveillance data should be maintained in the context of malaria elimination efforts. Public Library of Science 2020-05-15 /pmc/articles/PMC7228107/ /pubmed/32413069 http://dx.doi.org/10.1371/journal.pone.0231587 Text en © 2020 Diallo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Diallo, Mamadou Alpha
Badiane, Aida Sadikh
Diongue, Khadim
Sakandé, Linda
Ndiaye, Mouhamadou
Seck, Mame Cheikh
Ndiaye, Daouda
A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title_full A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title_fullStr A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title_full_unstemmed A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title_short A twenty-eight-year laboratory-based retrospective trend analysis of malaria in Dakar, Senegal
title_sort twenty-eight-year laboratory-based retrospective trend analysis of malaria in dakar, senegal
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228107/
https://www.ncbi.nlm.nih.gov/pubmed/32413069
http://dx.doi.org/10.1371/journal.pone.0231587
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