SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models

Bone marrow stroma influences metastatic prostate cancer (PCa) progression, latency, and recurrence. At sites of PCa bone metastasis, cancer-associated fibroblasts and tumor-associated macrophages interact to establish a perlecan-rich desmoplastic stroma. As a heparan sulfate proteoglycan, perlecan...

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Detalles Bibliográficos
Autores principales: Brasil da Costa, Fabio Henrique, Lewis, Michael S., Truong, Anna, Carson, Daniel D., Farach-Carson, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228113/
https://www.ncbi.nlm.nih.gov/pubmed/32413029
http://dx.doi.org/10.1371/journal.pone.0230354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228113/
https://www.ncbi.nlm.nih.gov/pubmed/32413029
http://dx.doi.org/10.1371/journal.pone.0230354

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