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Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer

Mounting evidence suggests that the gut microbiota contribute to colorectal cancer (CRC) tumorigenesis, in which the symbiotic Fusobacterium nucleatum (Fn) selectively increases immunosuppressive myeloid-derived suppressor cells (MDSCs) to hamper the host’s anticancer immune response. Here, a specif...

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Detalles Bibliográficos
Autores principales: Dong, Xue, Pan, Pei, Zheng, Di-Wei, Bao, Peng, Zeng, Xuan, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228756/
https://www.ncbi.nlm.nih.gov/pubmed/32440552
http://dx.doi.org/10.1126/sciadv.aba1590