Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq

The identification of autoantigens remains a critical challenge for understanding and treating autoimmune diseases. Autoimmune polyendocrine syndrome type 1 (APS1), a rare monogenic form of autoimmunity, presents as widespread autoimmunity with T and B cell responses to multiple organs. Importantly,...

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Detalles Bibliográficos
Autores principales: Vazquez, Sara E, Ferré, Elise MN, Scheel, David W, Sunshine, Sara, Miao, Brenda, Mandel-Brehm, Caleigh, Quandt, Zoe, Chan, Alice Y, Cheng, Mickie, German, Michael, Lionakis, Michail, DeRisi, Joseph L, Anderson, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228772/
https://www.ncbi.nlm.nih.gov/pubmed/32410729
http://dx.doi.org/10.7554/eLife.55053

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