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Alteration of Protein Binding Affinities by Aqueous Two-Phase Systems Revealed by Pressure Perturbation

Interactions between proteins and ligands, which are fundamental to many biochemical processes essential to life, are mostly studied at dilute buffer conditions. The effects of the highly crowded nature of biological cells and the effects of liquid-liquid phase separation inducing biomolecular dropl...

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Detalles Bibliográficos
Autores principales:	Oliva, Rosario, Banerjee, Sudeshna, Cinar, Hasan, Ehrt, Christiane, Winter, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228918/ https://www.ncbi.nlm.nih.gov/pubmed/32415277 http://dx.doi.org/10.1038/s41598-020-65053-6

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