Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity

Childhood acute lymphoblastic leukemia (cALL) is the most common pediatric cancer. It is characterized by bone marrow lymphoid precursors that acquire genetic alterations, resulting in disrupted maturation and uncontrollable proliferation. More than a dozen molecular subtypes of variable severity ca...

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Detalles Bibliográficos
Autores principales: Caron, Maxime, St-Onge, Pascal, Sontag, Thomas, Wang, Yu Chang, Richer, Chantal, Ragoussis, Ioannis, Sinnett, Daniel, Bourque, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228968/
https://www.ncbi.nlm.nih.gov/pubmed/32415257
http://dx.doi.org/10.1038/s41598-020-64929-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228968/
https://www.ncbi.nlm.nih.gov/pubmed/32415257
http://dx.doi.org/10.1038/s41598-020-64929-x

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