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Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs

Long non-coding RNAs (lncRNAs) are components of epigenetic control mechanisms that ensure appropriate and timely gene expression. The functions of lncRNAs are often mediated through associated gene regulatory activities, but how lncRNAs are distinguished from other RNAs and recruit effector complex...

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Detalles Bibliográficos
Autores principales: Thillainadesan, Gobi, Xiao, Hua, Holla, Sahana, Dhakshnamoorthy, Jothy, Jenkins, Lisa M. Miller, Wheeler, David, Grewal, Shiv I. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229227/
https://www.ncbi.nlm.nih.gov/pubmed/32415063
http://dx.doi.org/10.1038/s41467-020-16280-y