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Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4

Cooperation between DNA polymerases and DNA sliding clamp proteins is essential for DNA replication and repair. However, it is still challenging to clarify the binding mechanism and the movements of Y-family DNA polymerase IV (DPO4) on the proliferating cell nuclear antigen (PCNA) ring. Here we deve...

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Detalles Bibliográficos
Autores principales: Chu, Wen-Ting, Suo, Zucai, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229285/
https://www.ncbi.nlm.nih.gov/pubmed/32422591
http://dx.doi.org/10.1016/j.isci.2020.101117