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Copper Oxide Nanoparticles Induce Oxidative DNA Damage and Cell Death via Copper Ion-Mediated P38 MAPK Activation in Vascular Endothelial Cells

BACKGROUND: Inhaled nanoparticles can cross pulmonary air–blood barrier into circulation and cause vascular endothelial injury and progression of cardiovascular disease. However, the molecular mechanism underlying the vascular toxicity of copper oxide nanoparticles (CuONPs) remains unclear. We have...

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Detalles Bibliográficos
Autores principales:	He, Hui, Zou, Zhen, Wang, Bin, Xu, Ge, Chen, Chengzhi, Qin, Xia, Yu, Chao, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229313/ https://www.ncbi.nlm.nih.gov/pubmed/32494130 http://dx.doi.org/10.2147/IJN.S241157

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