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Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature

INTRODUCTION: ColorectaI carcinoma is extremely rare in children and presents with a poor prognosis. PRESENTATION OF CASE: The present report describes the case of a 14-year old male child who presented with complaints of general weakness and recurrent abdominal pain, caused by a mucinous adenocarci...

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Autores principales: Mremi, Alex, Yahaya, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229418/
https://www.ncbi.nlm.nih.gov/pubmed/32417738
http://dx.doi.org/10.1016/j.ijscr.2020.04.030
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author Mremi, Alex
Yahaya, James J.
author_facet Mremi, Alex
Yahaya, James J.
author_sort Mremi, Alex
collection PubMed
description INTRODUCTION: ColorectaI carcinoma is extremely rare in children and presents with a poor prognosis. PRESENTATION OF CASE: The present report describes the case of a 14-year old male child who presented with complaints of general weakness and recurrent abdominal pain, caused by a mucinous adenocarcinoma of the transverse colon (Dukes stage which was inoperable. DISCUSSION: Mucinous histopathological type is the most common type with increased ability to invade the adjacent stromal tissue. This biological behaviour has been reported to be attributable to its aggressive behaviour. Additionally, delay of diagnosis of colorectal carcinoma in children accounts for the advanced disease at diagnosis. CONCLUSION: Colorectal carcinoma occurring in both children and adolescents usually have poor prognosis because of not having specific symptoms which contributes to delay of diagnosis. Mimicking of its symptoms with other non-malignant conditions such as intestinal obstruction and acute appendicitis also has been found to contribute to delay of diagnosis as it was in our present case.
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spelling pubmed-72294182020-05-20 Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature Mremi, Alex Yahaya, James J. Int J Surg Case Rep Article INTRODUCTION: ColorectaI carcinoma is extremely rare in children and presents with a poor prognosis. PRESENTATION OF CASE: The present report describes the case of a 14-year old male child who presented with complaints of general weakness and recurrent abdominal pain, caused by a mucinous adenocarcinoma of the transverse colon (Dukes stage which was inoperable. DISCUSSION: Mucinous histopathological type is the most common type with increased ability to invade the adjacent stromal tissue. This biological behaviour has been reported to be attributable to its aggressive behaviour. Additionally, delay of diagnosis of colorectal carcinoma in children accounts for the advanced disease at diagnosis. CONCLUSION: Colorectal carcinoma occurring in both children and adolescents usually have poor prognosis because of not having specific symptoms which contributes to delay of diagnosis. Mimicking of its symptoms with other non-malignant conditions such as intestinal obstruction and acute appendicitis also has been found to contribute to delay of diagnosis as it was in our present case. Elsevier 2020-05-11 /pmc/articles/PMC7229418/ /pubmed/32417738 http://dx.doi.org/10.1016/j.ijscr.2020.04.030 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mremi, Alex
Yahaya, James J.
Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title_full Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title_fullStr Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title_full_unstemmed Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title_short Advanced mucinous colorectal carcinoma in a 14-year old male child: A case report and review of the literature
title_sort advanced mucinous colorectal carcinoma in a 14-year old male child: a case report and review of the literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229418/
https://www.ncbi.nlm.nih.gov/pubmed/32417738
http://dx.doi.org/10.1016/j.ijscr.2020.04.030
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