Investigating the inhibitory effect of miR-34a, miR-449a, miR-1827, and miR-106b on target genes including NOTCH1, c-Myc, and CCND1 in human T cell acute lymphoblastic leukemia clinical samples and cell line

OBJECTIVE(S): microRNAs are small non-coding molecules that regulate gene expression in various biological processes. T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy accompanied with genetic aberrations and accounts for 20% of children’s and adult’s ALL. Notch signaling pathway dysregula...

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Detalles Bibliográficos
Autores principales: Naderi, Tohid, Mohammadi-Yeganeh, Samira, Mohammadi-Hezaveh, Neda, Hadavi, Razie, Gharehbaghian, Ahmad, Vazifeh-Shiran, Nader, Fallah Azad, Vahid, Paryan, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229500/
https://www.ncbi.nlm.nih.gov/pubmed/32440325
http://dx.doi.org/10.22038/IJBMS.2019.40695.9615

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