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Fibroblast rejuvenation by mechanical reprogramming and redifferentiation
Over the course of the aging process, fibroblasts lose contractility, leading to reduced connective-tissue stiffness. A promising therapeutic avenue for functional rejuvenation of connective tissue is reprogrammed fibroblast replacement, although major hurdles still remain. Toward this, we recently...
Autores principales: | Roy, Bibhas, Yuan, Luezhen, Lee, Yaelim, Bharti, Aradhana, Mitra, Aninda, Shivashankar, G. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229653/ https://www.ncbi.nlm.nih.gov/pubmed/32350144 http://dx.doi.org/10.1073/pnas.1911497117 |
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