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Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI
R.PabI is a restriction DNA glycosylase that recognizes the sequence 5′-GTAC-3′ and hydrolyses the N-glycosidic bond of adenine in the recognition sequence. R.PabI drastically bends and unwinds the recognition sequence of double-stranded DNA (dsDNA) and flips the adenine and guanine bases in the rec...
Autores principales: | Miyazono, Ken-ichi, Wang, Delong, Ito, Tomoko, Tanokura, Masaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229829/ https://www.ncbi.nlm.nih.gov/pubmed/32232412 http://dx.doi.org/10.1093/nar/gkaa184 |
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