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Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

Human cytosolic leucyl-tRNA synthetase (hcLRS) is an essential and multifunctional enzyme. Its canonical function is to catalyze the covalent ligation of leucine to tRNA(Leu), and it may also hydrolyze mischarged tRNAs through an editing mechanism. Together with eight other aminoacyl-tRNA synthetase...

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Detalles Bibliográficos
Autores principales:	Liu, Ru-Juan, Long, Tao, Li, Hao, Zhao, JingHua, Li, Jing, Wang, MingZhu, Palencia, Andrés, Lin, JinZhong, Cusack, Stephen, Wang, En-Duo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229842/ https://www.ncbi.nlm.nih.gov/pubmed/32232361 http://dx.doi.org/10.1093/nar/gkaa189

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